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Physics-Informed Multiscale Digital Twin for Alzheimer's Disease

PIM-BrainTwin is presented as a physics-informed multiscale digital twin for Alzheimer's disease. It applies materials-science principles such as fatigue-like depletion, safety margins, and critical transitions to quantify residual compensatory capacity and system stability. The platform is open, modular, and federated, enabling formalization, comparison, and refinement of alternative mechanistic hypotheses.

Why it matters

Demonstrates application of digital twin approaches in precision medicine, extending modeling of complex biological systems.

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Original headline
Towards a physics-informed multiscale digital twin for precision medicine in Alzheimer's disease
Read the original: arXiv API — полнотекстовый поиск "digital twin"

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