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Operator Learning for Transcranial Focused Ultrasound Digital Twins
US & West ·
A new approach to modeling transcranial focused ultrasound based on operator learning is proposed: a coordinate-aware neural operator tFUSOperator that maps free-field pressure, skull anatomy, and treatment parameters to the intracranial field in a shared physical coordinate frame. This is the first operator-based formulation for tFUS field prediction.
Why it matters
Demonstrates the potential of operator learning for fast and accurate digital twins in medical applications, which could be adapted for other physical systems.
Growing interest in in-space servicing, manufacturing, and assembly has renewed attention on reliable metal joining for modular construction and on-orbit repair. Robotic welding is promising, but reduced-gravity and low-pressure operation remains poorly characterised and flight-like tests are…
Digital twins (DTs) can generate dense synthetic fingerprints for localization via ray tracing, yet the sim-to-real domain gap limits their direct use, particularly in cell-free millimeter-wave (mmWave) deployments where distributed geometries and blockage-induced sparsity widen the mismatch.
Catheter obstruction is the commonest cause of shunt failure; freehand insertion at Keen's point leaves the tip free in cerebrospinal fluid in only one case in ten. We built a digital twin that reconstructs skull, scalp, ear and ventricles from preoperative CT by deterministic geometry, searches…